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J&JPRD receives FDA Complete Response Letter for tapentadol ER tablets NDA

July 21, 2017

The researchers use an experimental model of lab rats that produces traits that mimic periodic sleep apnea. Using state-of-the-art techniques and equipment in the MU Dalton Cardiovascular Research Center, the researchers are able to identify specific cells and pathways within the brain that are involved in responses to hypoxia. Researchers hope the information can be used to develop drugs or procedures to correct or slow the dangerous effects of sleep apnea.

"Working together, we each bring different skills and ways of looking at the problem, which increases our ability to answer the important questions in this field," Hasser said.

While only in the first year of the four-year grant, the researchers have already advanced knowledge on how the brain adapts to diminished oxygen. Results of their initial experiments were recently published in the scientific journal, Neuroscience.

Source: University of Missouri-Columbia